In the complex landscape of mental health research, a new peer-reviewed Viewpoint review sheds light on an underexplored genetic player: the trace amine-associated receptor 1 (TAAR1). Published in Genomic Psychiatry (ISSN: 2997-2388, Genomic Press, New York), this thought-provoking analysis suggests that mutations in the TAAR1 gene may be a crucial piece of the puzzle in understanding and treating neuropsychiatric disorders.