Latest Diabetes News

  • New Food-Sharing Compass platform to be launched at the final event of CULTIVATE project

    The new platform, known as the Food-Sharing Compass, will be unveiled at the final event of the EU-funded CULTIVATE project which created it for the wider food-sharing community.

  • New surgical technique enlarges aortic roots for larger valve implants

    When replacing the aortic valve, a small aortic root can limit the size of the prosthetic valve that can be implanted.

  • Does adding yeast to whey protein help muscle recovery after exercise?

    The yeast-whey protein blend shows potential in aiding muscle recovery after exercise-induced damage, yet its effectiveness compared to whey alone is uncertain.

  • Invisible no more: New treatment avenue unlocked for deadliest lung cancer

    Researchers have uncovered a previously overlooked immune cell that can recognize and kill small cell lung cancer, the most aggressive form of the disease globally.

  • invIOs publishes positive clinical data on CBL-B-silenced autologous cell therapy APN401 in peer-reviewed journal

    invIOs GmbH (“invIOs”), a privately held biotechnology company developing innovative cancer immunotherapies, today announced the publication of new clinical data with its autologous PBMC (peripheral blood mononuclear cell) therapy APN401 in the peer-reviewed journal, Molecular Therapy Oncology.

  • Drug-coated balloons offer an alternative to permanent heart stents

    Thousands of heart patients could be treated without having a metal stent permanently implanted in their arteries - according to research from the University of East Anglia (UEA).

  • Parents know fruit and vegetables are healthy, but many underestimate how much children need

    A qualitative study involving 15 Swedish parents found that although most recognized the health benefits of fruit and vegetables, many underestimated recommended daily intake and considered serving vegetables at dinner sufficient. Researchers identified four overlapping parental roles influencing children's eating habits and suggested that clearer guidance on quantities, serving frequency, and practical feeding approaches could help families improve consumption.

  • Bisphenol mixtures alter breast tissue development in lab-grown human models

    Exposure to common chemicals may alter how normal human breast tissue develops, according to a new study from researchers at Tufts University School of Medicine and Boston University

  • New study could help reduce radiation exposure during cardiac CT scans

    A new study at The University of Texas at Arlington could help substantially reduce the amount of radiation heart patients receive during imaging procedures without sacrificing diagnostic accuracy.

  • Study identifies priority genes for safer prescribing in older Chinese patients

    A research team has identified three genes that could help prioritize pharmacogenomic testing for older adults in China who receive multiple medications.

  • Ozempic and Wegovy linked to rare risk of sudden vision loss

    Popular diabetes and weight loss drugs such as Ozempic and Wegovy have been linked to a slightly increased risk of a rare condition that can cause sudden, potentially permanent vision loss. Although the risk remains very low, Rutgers researchers say the findings warrant attention as millions of people turn to GLP-1 medications.

  • Vitamin D drug may help crack pancreatic cancer’s protective shield

    A vitamin D analog may help break down pancreatic cancer’s protective defenses, potentially making tumors more vulnerable to chemotherapy and immune attack. A small clinical trial found encouraging responses, especially in patients whose tumors had high levels of the vitamin D receptor.

  • Scientists find a way to break pancreatic cancer’s protective shield

    Researchers found that blocking IL1RAP could disrupt a powerful inflammatory network that helps pancreatic cancer survive treatment. In preclinical experiments, the approach reduced tumor-protecting cells and fibrosis while boosting the activity of cancer-fighting T cells. That could make chemotherapy and immunotherapy more effective.

  • Scientists discover the deep sleep circuit that builds muscle, burns fat, and boosts the brain

    Researchers have identified the brain circuitry that links deep sleep with the release of growth hormone, revealing how the two regulate each other. The newly discovered feedback loop helps explain why poor sleep can interfere with growth, muscle repair, fat metabolism, and brain function. Understanding this system could pave the way for new therapies for sleep disorders and diseases tied to metabolism and the brain, including Alzheimer's and Parkinson's.

  • Scientists finally crack an “undruggable” pancreatic cancer target and nearly double survival

    For decades, pancreatic cancer has been one of the most lethal cancers, with few effective treatment options. A new drug, daraxonrasib, targets the KRAS mutation that fuels most pancreatic tumors—something many scientists once thought couldn't be done. In a major clinical trial, the treatment nearly doubled survival for patients with advanced disease and reduced the risk of death by 60%.

  • One fat helped pancreatic cancer grow while another cut disease in half

    A surprising new study suggests that when it comes to pancreatic cancer, the kind of fat you eat may matter more than how much. Researchers found that oleic acid—the main fat in olive oil and several other common foods—sped up tumor growth in mice predisposed to pancreatic cancer, while omega-3-rich fats from fish oil dramatically slowed disease development.

  • Scientists discover sleep switch that builds muscle, burns fat, and boosts brainpower

    Deep sleep does far more than rest the body — it activates a powerful brain-driven system that controls growth hormone, fueling muscle and bone strength, metabolism, and even mental performance. Scientists have now mapped the neural circuits behind this process, uncovering a delicate feedback loop in which sleep boosts growth hormone, and that same hormone helps regulate wakefulness.

  • Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy

    Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control.

  • Scientists find hidden pathways pancreatic cancer uses to spread

    Researchers have discovered how pancreatic cancer reprograms its surroundings to spread quickly and stealthily. By using a protein called periostin, the tumor remodels nearby tissue and invades nerves, which helps cancer cells travel and form metastases. This process also creates a tough, fibrous barrier that makes treatments less effective. Targeting periostin could help stop this invasion before it starts.

  • Northwestern Medicine’s new antibody wakes the immune system against pancreatic cancer

    Pancreatic cancer uses a sugar-coated disguise to evade the immune system, helping explain why it’s so hard to treat. Northwestern scientists discovered this hidden mechanism and created an antibody that strips away the tumor’s protective signal. In animal tests, immune cells sprang back into action and tumors grew much more slowly. The team is now refining the therapy for future human trials.

  • Dementia-like clumps found in cells before cancer strikes

    Researchers found that pancreatic pre-cancer cells mimic dementia by forming clumps of proteins due to faulty recycling processes. These insights could shed light on why pancreatic cancer develops so aggressively and why it is difficult to treat. By studying overlaps with neurological diseases, scientists hope to identify new strategies for prevention and treatment.

  • The sleep switch that builds muscle, burns fat, and boosts brainpower

    UC Berkeley researchers mapped the brain circuits that control growth hormone during sleep, uncovering a feedback system where sleep fuels hormone release, and the hormone regulates wakefulness. The discovery helps explain links between poor sleep, obesity, diabetes, and cognitive decline, while opening new paths for treating sleep and metabolic disorders.

  • This tiny implant could save diabetics from silent, deadly crashes

    MIT engineers have developed a tiny implantable device that could revolutionize emergency treatment for people with Type 1 diabetes. The device contains a powdered form of glucagon and can be remotely triggered—either manually or automatically by a glucose monitor—to release the hormone when blood sugar drops too low. This offers a potentially life-saving safety net, especially during sleep or for young children.

  • Biologists identify targets for new pancreatic cancer treatments

    Cryptic peptides, which are expressed in pancreatic cancer cells, could be promising targets for T-cell therapies that attack pancreatic tumors, according to a new study.

  • Low blood sugar contributes to eye damage and vision loss in diabetic retinopathy; experimental drug may help treat condition

    Scientists say they have determined that low blood sugar, or hypoglycemia, may promote a breakdown of the blood-retinal barrier, an important boundary that regulates the flow of nutrients, waste and water in and out of the retina.

  • In pancreatic cancer, a race against time

    Scientists have found a way to 'intercept' pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to prevent pancreatic cancer from forming in the first place.

  • Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer

    Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy.

  • Receiving low-glucose alerts improves diabetic drivers' safety on the road

    A Japanese study has found that the use of continuous glucose monitoring (CGM) devices, equipped with sensors that alert diabetics when their blood sugar levels drop, can potentially make diabetic drivers safer on the road. Those who used the devices had lower incidences of low blood sugar and reported increased confidence in driving.

  • Toward improved early detection of pancreatic cancer

    Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13% of patients who are diagnosed with PC surviving for 5 years or more after initial diagnosis. Early detection of PC is the primary concern of most PC research, as it has the potential to make a substantial difference to the treatment and survival of patients. Survival rates, however, remain poor due to the vague nature of the symptoms associated with early-stage PC, and subsequently the late-stage of the disease at diagnosis. Now researchers are focusing on pancreatic cystic lesions to tackle the crucial issue of identifying patients who are at high-risk of developing pancreatic cancer, to improve survival rates.

  • Diabetes can drive the evolution of antibiotic resistance

    Researchers have proven that antibiotic-resistant strains of a harmful bacteria thrive in a diabetic infection environment.

  • New blood test identifies hard-to-detect pancreatic cancer with 85% accuracy

    A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers.

  • Type 1 diabetes: Hybrid closed-loop and open-loop systems compared

    People with type 1 diabetes require continuous insulin treatment and must regularly measure their glucose levels. With open-loop therapies, insulin administration is manually controlled, while hybrid closed-loop systems automatically regulate insulin delivery. A study showed that hybrid closed-loop systems offer improved long-term blood sugar values (HbA1c levels) and a lower risk of hypoglycemic coma, but lead to a higher rate of diabetic ketoacidosis.

  • Pancreatic cancer immune map provides clues for precision treatment targeting

    Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies, and clues behind why these tumors don't respond to existing immunotherapies.

  • Protein degradation strategy offers new hope in cancer therapy

    A team of scientists has used a novel approach to identify protein degraders that target Pin1, a protein involved in pancreatic cancer development.

  • Researchers show how gut hormones control aging in flies and how it relates to human biology

    The discovery of a gut-to-brain regulation pathway in flies calls for additional consideration on how certain medications, especially GLP-1 agonists, can be used to treat obesity and diabetes in humans.

  • A new injectable to prevent and treat hypoglycemia

    People with diabetes take insulin to lower high blood sugar. However, if glucose levels plunge too low -- from taking too much insulin or not eating enough sugar -- people can experience hypoglycemia, which can lead to dizziness, cognitive impairment, seizures or comas. To prevent and treat this condition, researchers report encapsulating the hormone glucagon. In mouse trials, the nanocapsules activated when blood sugar levels dropped dangerously low and quickly restored glucose levels.

  • Pancreatic cancer: Study finds most early staging inaccurate

    Staging of patients with early pancreatic cancer is inaccurate as much as 80% of the time, according to a new study. The finding underscores the urgent need for advancements in diagnostic technology and staging, which could significantly alter early pancreatic cancer treatment and research.

  • How thyroid hormone fuels the drive to explore

    Research in mice sheds light on how thyroid hormone alters wiring in the brain. Findings reveal that thyroid hormone syncs up the brain and body to drive exploratory behavior. Researchers say their work could illuminate new treatments for certain psychiatric conditions.

  • Link discovered between sensory neurons and breast cancer metastasis

    Researchers found a 'neuro-cancer axis' may promote spread of breast cancer. They also found that an FDA-approved anti-nausea medication may prevent it.

  • New tools reveal neuropeptides, not neurotransmitters, encode danger in the brain

    Scientists created new tools to study brain messenger proteins called neuropeptides in the brains of behaving animals, discovering they are the primary messengers in the fear circuit in mouse brains, and that multiple neuropeptides work together to achieve this--explaining why some clinical trials that target just one neuropeptide have failed. The new tools and findings can be used to direct drug development for fear-related neurological disorders like PTSD and anxiety, design better painkillers, and uncover new information for other neural circuits in the brain.

  • New 3D technique reveals precancerous pancreatic lesions

    Researchers have developed a 3D genomic profiling technique to identify small precancerous lesions in the pancreas -- called pancreatic intraepithelial neoplasias (PanINs) -- that lead to one of the most aggressive, deadly pancreatic cancers.

  • How targeted nutrients can fight cancer

    An international research team has discovered a new way to effectively treat cancer, by using nutrients to reactivate suppressed metabolic pathways in cancer cells.

  • Alarming trends call for action to define the future role of food in nation's health

    The cost of nutritious food and the lack of access to it are of significant concern to U.S. consumers. New public opinion poll and expert analysis reflect crucial need to make healthy food accessible to avert projected crisis in cardiovascular disease incidence, costs.

  • New therapeutic targets to fight type 2 diabetes

    One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels. This is because in these insulin-resistant patients, glucose production by the liver is triggered, a process that is still full of questions for the scientific community. Now, a review article presents a comprehensive overview of the most important advances in understanding this mechanism.

  • Breaking down barriers: ROCK2 inhibition facilitates drug delivery in fibrotic pancreatic cancer

    Scientists developed a human pancreatic cancer fibrotic barrier 3D cell-culture model to assess treatments for pancreatic ductal adenocarcinoma. By targeting the ROCK2 pathway, they achieved a notable decrease in fibrosis and enhanced tissue permeability to drugs, offering promising avenues for overcoming treatment obstacles in pancreatic cancer.