A Nature study projects that millions born after 1960 will face unprecedented lifetime exposure (ULE) to climate extremes, such as heatwaves, droughts, and floods. The risks grow with global warming and disproportionately impact socioeconomically vulnerable populations.

Dental caries, or tooth decay, is a common oral health condition that often causes significant pain and discomfort and may even lead to tooth loss.

A new study puts the spotlight on the rising burden of ischemic heart disease across Southeast Asia, East Asia and Oceania, and calls for localized, equity-focused interventions in these regions.

Researchers identified 11 genetic loci linked to the age at which infants start walking, revealing that this milestone is influenced by thousands of common genetic variants. These genetic factors also correlate with brain development, cognitive traits, and neurodevelopmental conditions like ADHD.

Announcing a new publication for Acta Materia Medica journal. A preclinical study has developed a precision nano-intervention strategy targeting tumor-associated nerves to destroy nerve-fueled tumor growth in pancreatic cancer.

A single blood test, designed to pick up chemical signals indicative of the presence of many different types of cancer, could potentially thwart progression to advanced disease while the malignancy is still at an early stage and amenable to treatment in up to half of cases, suggests a modelling study published in the open access journal BMJ Open.

A study including researchers from the University of Arizona Health Sciences and published in the Journal of Exposure Science & Environmental Epidemiology found that firefighters had higher concentrations of certain per- and polyfluoroalkyl substances, or PFAS, and health care workers had moderate elevations of PFAS in their blood with significantly higher odds of two specific PFAS when compared with other essential workers.

While extremely rare, encephalopathy (a condition affecting brain function) triggered by mutations in the UBA5 gene has devastating impacts, with affected individuals reaching few developmental milestones and experiencing frequent and early-onset seizures.

University of Cincinnati engineers created a new device to help doctors diagnose depression and anxiety.

Eyes may be the window to the soul, but a person's biological age could be reflected in their facial characteristics. Investigators from Mass General Brigham developed a deep learning algorithm called FaceAge that uses a photo of a person's face to predict biological age and survival outcomes for patients with cancer.

A new strategy may help prevent or slow the progression of Type 1 diabetes.

A recent study found that six cardiometabolic risk groups previously identified in middle-aged individuals can also be applied to older adults without diabetes. Using data from the KORA F4/FF4 study of people aged 61 to 82, researchers identified clusters with varying risks of developing type 2 diabetes and related complications. One cluster, marked by high inflammatory load and insulin-resistant fatty liver, showed particularly high risk. The study highlights the importance of personalized risk assessment and early prevention strategies even in older age.

Eating a healthy diet as a child is linked to girls having their first menstrual period at an older age than those who consumed a less healthy diet, according to a new study. The findings remained unaltered by the girls' body mass index or height, both of which have been associated with the earlier onset of periods. The study has implications for health in later life as it is well known that women who started their periods at an early age may be at higher risk for diabetes, obesity, breast cancer and diseases of the heart and blood vessels.

Scientists say they have determined that low blood sugar, or hypoglycemia, may promote a breakdown of the blood-retinal barrier, an important boundary that regulates the flow of nutrients, waste and water in and out of the retina.

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 Diabetes, or T2D. The research team focused on the significance of deubiquitinating enzymes, or DUBs, in regulating mitochondrial dynamics within skeletal muscle. Findings suggest that mitochondrial fragmentation can bypass defects in mitophagy, the process by which cells remove damaged mitochondria, to sustain skeletal muscle quality control in patients with T2D. This adaptation may help maintain mitochondrial function despite impaired mitophagy.

Researchers have developed a revolutionary new way to find out the 'true age' of your heart using MRI. A new study shows how an MRI scan can reveal your heart's functional age -- and how unhealthy lifestyles can dramatically accelerate this figure. It is hoped that the findings could transform how heart disease is diagnosed -- offering a lifeline to millions by catching problems before they become deadly. The team say their cutting-edge technique is a 'game changer'.

Semaglutide effectively treats liver disease in two thirds of patients, new research has found.

Researchers investigated the combined effects of bazedoxifene and conjugated estrogens in rat models as an alternative to tamoxifen.

Persistently high blood sugar and insulin resistance significantly increased the risk of worsening functional and structural heart damage during growth from adolescence to young adulthood, a new study shows.

It's no secret that our waistlines often expand in middle-age, but the problem isn't strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases. Exactly how age transforms a six pack into a softer stomach, however, is murky. New research shows how aging shifts stem cells into overdrive to create more belly fat.

Using their novel FRESH 3D bioprinting technique, which allows for printing of soft living cells and tissues, a lab has built a tissue model entirely out of collagen.

Scientists have identified a simple, noninvasive method for assessing blood glucose regulation using continuous glucose monitoring (CGM) data. Their approach, which tracks glucose fluctuations, outperforms traditional markers in predicting diabetes risk. To expand accessibility, they have developed a web application for easy calculation of CGM-based indices.

A data-informed approach to scheduling patient encounters with clinicians can reduce risks associated with diabetes management by up to 19.4%, especially for underserved populations, says new research.

Drugs like Ozempic, other blood sugar-reducing medications, may stave off dementia.

Researchers found that by December 2023, more than 1 in 3 of the medications being started for type 2 diabetes treatment were GLP-1RA-based medications.

A new study has found children born to mothers who experienced gestational diabetes (GDM) during pregnancy are more likely to develop attention-deficient hyperactive disorder (ADHD) and externalizing behavior.

Data-sparse method opens door to personalized nutrition -- without the stool samples.

Researchers conducted a large-scale epidemiological study to explore the potential health benefits of high muscle strength in preventing type 2 diabetes (T2D) across varying levels of genetic risk. The study found that higher muscle strength was associated with over 40% lower risk of T2D, regardless of genetic susceptibility to T2D. The study highlights the importance of maintaining or improving muscle strength as a key strategy for preventing T2D.

Two undergraduate medicine students have led a major study examining how cardioprotective glucose-lowering therapies -- medications that lower blood sugar and reduce the risk of heart disease in people with diabetes -- affect the risk of developing dementia.

The intermittent fasting diet, which involves periods of severe calorie restriction, may be on the way out, as research is suggesting that rather than drastically reducing calories, people can achieve similar metabolic benefits by cutting back on carbs.

Research shows that the biological parents' genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease.

New research has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes -- not the presence of certain fats, but their suppression. The study challenges the conventional belief that a type of fat called ceramides accumulates in blood vessels causing inflammation and health risks. Instead, their findings reveal that when ceramides decrease in endothelial cells lining blood vessels, it can be damaging and cause chronic illnesses. Ironically, the findings could ultimately lead to therapies that maintain high levels of these protective lipids in patients with obesity.

Nearly 40% of patients diagnosed with type 2 diabetes imperil their health by stopping their medication within the first year, diabetes experts warn.

A research team has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes. The results show that high blood pressure can lead to abnormalities in the podocytes, specialized cells in the renal filter, even without other pre-existing conditions such as diabetes. The results underline the importance of early detection and consistent treatment of high blood pressure in order to prevent kidney damage.

Wearable mobile health technology could help people with Type 2 Diabetes (T2D) to stick to exercise regimes that help them to keep the condition under control, a new study reveals. An international team studied the behavior of recently-diagnosed T2D patients in Canada and the UK as they followed a home-based physical activity program, with some participants wearing a smartwatch paired with a health app on their smartphone.

A research team says high blood sugar levels appear to weaken function in key part of brain, mimicking Alzheimer's.

Scientists used advanced data analysis and machine learning to identify the viral proteins that may trigger autoimmune disorders such as type 1 diabetes and rheumatoid arthritis.

In 2010, a researcher was pouring over research data when he discovered something he thought was odd: His data showed that at 6 months of age, formula-fed babies born of mothers who were categorized as medically obese weighed about 5% units less fat than breastfed babies in the same dataset. That discovery struck him as unusual and led him on a research journey to better understand breast milk. Now, he's studying the connections between maternal gestational diabetes, breastfeeding and infant health.

Exposure to antibiotics during a key developmental window in infancy can stunt growth of insulin-producing cells in the pancreas and may boost risk of diabetes later in life, new research in mice suggests. The study also pinpoints specific microorganisms that may help those critical cells proliferate.

An innovative platform replicates pancreatic functions, transforming diabetes therapy.

Researchers show that using continuous glucose monitors can help measure glucose accurately during DKA and potentially prevent ICUs from being overwhelmed.

When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life. A new study sheds light on changes to the fetus's bile acid, which affects how liver disease develops and progresses.

Although there is no cure, diabetic retinal disease treatment has improved over the past two decades.

A sedentary lifestyle such as watching TV (two or more hours daily) may be a key factor in the risk of developing heart and blood vessel diseases, according to an analysis of health records from a large biomedical database.

New research suggests that automated insulin delivery (AID) systems are safe and effective for use by older adults with type 1 diabetes. The findings counter common assumptions that older adults would struggle to use the more advanced technology employed in the medical devices.