A genetic mutation that helps animals like yaks and Tibetan antelopes survive at high altitudes may hold the key to repairing nerve damage in conditions such as cerebral paralysis and multiple sclerosis (MS).

Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare.

An international team of researchers has achieved a breakthrough in the production of doxorubicin, a vital chemotherapy agent.

Persons under stress may have a harder time spatially orienting themselves. Researchers in Bochum have discovered why.

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization and immune function.

For their discovery of genomic imprinting, developmental biologists Davor Solter and Azim Surani will receive the 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, endowed with €120,000, on March 14 at Frankfurt’s Paulskirche.

Dementia, global trends, community attitudes, conscientious objections by doctors and health facilities, Indigenous perspectives, and organ donation are among agenda topics for the International Conference on Assisted Dying and Other End of Life Care (ICEL5) at QUT next month.

A new, national analysis published in the Aesthetic Surgery Journal suggests the future growth of aesthetic surgery may lie far from traditional luxury markets.

Artificial intelligence could make cancer diagnosis safer and fairer by learning when to defer to human pathologists without overloading them, according to researchers from the University of Surrey and Monash University.

A new research paper was published in Volume 18 of Aging-US on March 2, 2026, titled "D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice."

Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control.

Researchers have discovered how pancreatic cancer reprograms its surroundings to spread quickly and stealthily. By using a protein called periostin, the tumor remodels nearby tissue and invades nerves, which helps cancer cells travel and form metastases. This process also creates a tough, fibrous barrier that makes treatments less effective. Targeting periostin could help stop this invasion before it starts.

Pancreatic cancer uses a sugar-coated disguise to evade the immune system, helping explain why it’s so hard to treat. Northwestern scientists discovered this hidden mechanism and created an antibody that strips away the tumor’s protective signal. In animal tests, immune cells sprang back into action and tumors grew much more slowly. The team is now refining the therapy for future human trials.

Researchers found that pancreatic pre-cancer cells mimic dementia by forming clumps of proteins due to faulty recycling processes. These insights could shed light on why pancreatic cancer develops so aggressively and why it is difficult to treat. By studying overlaps with neurological diseases, scientists hope to identify new strategies for prevention and treatment.

UC Berkeley researchers mapped the brain circuits that control growth hormone during sleep, uncovering a feedback system where sleep fuels hormone release, and the hormone regulates wakefulness. The discovery helps explain links between poor sleep, obesity, diabetes, and cognitive decline, while opening new paths for treating sleep and metabolic disorders.

MIT engineers have developed a tiny implantable device that could revolutionize emergency treatment for people with Type 1 diabetes. The device contains a powdered form of glucagon and can be remotely triggered—either manually or automatically by a glucose monitor—to release the hormone when blood sugar drops too low. This offers a potentially life-saving safety net, especially during sleep or for young children.

Cryptic peptides, which are expressed in pancreatic cancer cells, could be promising targets for T-cell therapies that attack pancreatic tumors, according to a new study.

Scientists say they have determined that low blood sugar, or hypoglycemia, may promote a breakdown of the blood-retinal barrier, an important boundary that regulates the flow of nutrients, waste and water in and out of the retina.

Scientists have found a way to 'intercept' pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to prevent pancreatic cancer from forming in the first place.

Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy.

A Japanese study has found that the use of continuous glucose monitoring (CGM) devices, equipped with sensors that alert diabetics when their blood sugar levels drop, can potentially make diabetic drivers safer on the road. Those who used the devices had lower incidences of low blood sugar and reported increased confidence in driving.

Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13% of patients who are diagnosed with PC surviving for 5 years or more after initial diagnosis. Early detection of PC is the primary concern of most PC research, as it has the potential to make a substantial difference to the treatment and survival of patients. Survival rates, however, remain poor due to the vague nature of the symptoms associated with early-stage PC, and subsequently the late-stage of the disease at diagnosis. Now researchers are focusing on pancreatic cystic lesions to tackle the crucial issue of identifying patients who are at high-risk of developing pancreatic cancer, to improve survival rates.

Researchers have proven that antibiotic-resistant strains of a harmful bacteria thrive in a diabetic infection environment.

A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers.

People with type 1 diabetes require continuous insulin treatment and must regularly measure their glucose levels. With open-loop therapies, insulin administration is manually controlled, while hybrid closed-loop systems automatically regulate insulin delivery. A study showed that hybrid closed-loop systems offer improved long-term blood sugar values (HbA1c levels) and a lower risk of hypoglycemic coma, but lead to a higher rate of diabetic ketoacidosis.

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies, and clues behind why these tumors don't respond to existing immunotherapies.

Imagine an insulin that became more or less effective when your blood sugar levels went up or down.

This incredible keto turtle cheesecake is a decadent dessert for anyone on a keto diet or low-carb journey.

This content originally appeared on Everyday Health. Republished with permission.By Barbie Cervoni, RD, CDE Medically Reviewed by Lynn Grieger, RDN, CDCES If you have type 2 diabetes, at some point someone has probably looked disapprovingly at your toast and told you, “You can’t eat that.” Ignoring for a moment the audacity of this know-it-all, most

Chronic kidney disease can lead to inaccurate A1C readings due to anemia and changes in red blood cell production.

If you have unused diabetes supplies that you no longer need, don’t throw them away. There are ways you can donate your supplies and help others with diabetes across the world.

Why muscle health is a big deal in type 2 diabetes, and what to do about it.

Satisfy your sweet tooth guilt-free with this homemade Sugar-Free Snickers recipe!

Participating in clinical trials is a way for people with diabetes to be directly involved in the evolution of diabetes care.

You already know that consuming protein is essential in any diet. To maintain a healthy weight and heart, though, choose lean sources.

An investigational therapy could protect people with type 1 diabetes from low blood sugars overnight.

A team of scientists has used a novel approach to identify protein degraders that target Pin1, a protein involved in pancreatic cancer development.

The discovery of a gut-to-brain regulation pathway in flies calls for additional consideration on how certain medications, especially GLP-1 agonists, can be used to treat obesity and diabetes in humans.

People with diabetes take insulin to lower high blood sugar. However, if glucose levels plunge too low -- from taking too much insulin or not eating enough sugar -- people can experience hypoglycemia, which can lead to dizziness, cognitive impairment, seizures or comas. To prevent and treat this condition, researchers report encapsulating the hormone glucagon. In mouse trials, the nanocapsules activated when blood sugar levels dropped dangerously low and quickly restored glucose levels.

Staging of patients with early pancreatic cancer is inaccurate as much as 80% of the time, according to a new study. The finding underscores the urgent need for advancements in diagnostic technology and staging, which could significantly alter early pancreatic cancer treatment and research.

Research in mice sheds light on how thyroid hormone alters wiring in the brain. Findings reveal that thyroid hormone syncs up the brain and body to drive exploratory behavior. Researchers say their work could illuminate new treatments for certain psychiatric conditions.

Researchers found a 'neuro-cancer axis' may promote spread of breast cancer. They also found that an FDA-approved anti-nausea medication may prevent it.

Scientists created new tools to study brain messenger proteins called neuropeptides in the brains of behaving animals, discovering they are the primary messengers in the fear circuit in mouse brains, and that multiple neuropeptides work together to achieve this--explaining why some clinical trials that target just one neuropeptide have failed. The new tools and findings can be used to direct drug development for fear-related neurological disorders like PTSD and anxiety, design better painkillers, and uncover new information for other neural circuits in the brain.

Researchers have developed a 3D genomic profiling technique to identify small precancerous lesions in the pancreas -- called pancreatic intraepithelial neoplasias (PanINs) -- that lead to one of the most aggressive, deadly pancreatic cancers.

An international research team has discovered a new way to effectively treat cancer, by using nutrients to reactivate suppressed metabolic pathways in cancer cells.