AI-driven genomic analysis could help researchers identify existing drugs that may be repurposed for subtype-specific breast cancer treatment. The review proposes an interpretability-driven framework that links multi-omics data, mechanistic validation,…

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps make each person…

Researchers found that more than half of urban rats sampled from low-income communities in Salvador, Brazil, carried active pharmaceutical ingredients in their brain tissue. These pollutants were associated with altered…

Among the younger part of the population, sleep problems, anxiety, and depression are widespread and growing issues.

An 8-month low-calorie diet plus behavioral support helped older adults with overweight or obesity and persistent atrial fibrillation lose weight safely, with no intervention-related serious adverse events. However, the LOSE-AF…

A new preclinical study led by researchers at The University of Texas MD Anderson Cancer Center and Weill Cornell Medicine has uncovered genetic and cell-state adaptive mechanisms that drive resistance…

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

Younger generations appear to be experiencing poorer health earlier in life than previous generations, according to a review of studies comparing national birth cohort datasets involving tens of thousands of…

A small proof-of-concept RCT found that tocilizumab, an IL-6 receptor blocker, showed a non-significant but clinically suggestive pattern of improvement in difficult-to-treat depression linked to low-grade inflammation. The study found…

An artificial intelligence-based tool may help physicians determine which newly diagnosed multiple myeloma patients are most likely to benefit from specific therapies, including immunotherapy and stem cell transplantation.