Severe COVID-19 reactivates dormant viruses and may leave a lasting viral signature

A longitudinal study of 1,154 hospitalized COVID-19 patients found widespread reactivation of chronic Herpesviridae and Anelloviridae, with distinct viral patterns linked to disease severity, inflammation, and clinical outcomes. Anelloviridae also…

Continue ReadingSevere COVID-19 reactivates dormant viruses and may leave a lasting viral signature

Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target

Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants…

Continue ReadingGenetic analysis of 1 million people points to FNIP1 as a promising metabolic target