Researchers screened over 5,000 compounds and successfully pinpointed 70 existing drugs, including unexpected beta-lactam antibiotics, that effectively suppress Puumala orthohantavirus infection in human cells. This milestone drug-repurposing study provides an…

Melatonin reduced infection-related inflammation in human fetal membranes in an ex vivo model. The study suggests that this effect works partly through melatonin receptors and by suppressing the TLR4/MyD88/NF-κB pathway.

Nasal commensal viruses may worsen allergic rhinitis by activating type I IFN-linked neutrophils and NET formation. Ribavirin reduced nasal viral abundance and improved symptoms in mice and in a small…

University of West Florida Assistant Professor of Public Health Dr. Karishma Chhabria Unrue has been awarded a nearly $825,000 grant through the Florida Cancer Innovation Fund to lead a statewide…

Acute leukemias with chimeric fusion genes involving FET (FUS, EWSR1, and TAF15) family proteins and ETS (E26 transformation-specific)-like transcription factors often present with unique clinical and pathological characteristics.

Digital pathology (DP) is transitioning from an adjunct technology to an enterprise diagnostic platform in the United States. Despite accelerating clinical adoption, many laboratories face persistent barriers, including high capital…

The development of a pioneering gene therapy to treat a devastating, rare immune disorder led by UCL scientists is set to move into its next phase following promising early pre-clinical…

For women's health providers, the Dobbs decision that rescinded abortion rights wasn't just an abstract political event.

New commentary published in the Journal of the Royal Society of Medicine warns that current risk-based regulatory approaches to Artificial Intelligence (AI) in healthcare fall short in protecting patients, potentially…

Adelaide University researchers have carried out the first in-human trial of a new type of treatment for a leading cause of blindness in working age adults, with promising results.