Loneliness can reprogram the brain in ways that push alcohol consumption, reports a new preclinical study led by Northwestern University and the Salk Institute for Biological Studies.

Brain cells that produce the protective coating around nerve fibers can become dysfunctional with age and may actively contribute to cognitive decline, according to new research.

Researchers from the University of Turku in Finland and Gustave Roussy Institute in France have discovered a molecular mechanism that regulates whether the cells of an aggressive colorectal cancer are…

​Transplant medicine still depends on a limited supply of donor organs, while many retrieved grafts are discarded because ischemia, cold storage, and reperfusion can rapidly damage their cells.

Everyone knows the number. Eight hours. It sits on wellness dashboards, on pediatric handouts, on the label of the melatonin bottle in the medicine cabinet.

A scoping review of 54 studies found that coffee and several coffee-derived bioactive compounds influence pathways linked to skeletal muscle metabolism, including insulin signaling, mitochondrial function, oxidative stress, inflammation, glucose…

What did ordinary people really eat in premodern Japan, beyond the dishes described in cookbooks and the bones discarded at urban waste pits? Reconstructing past diets at the level of…

A narrative review found that moderate wine intake has repeatedly been associated with lower all-cause and cardiovascular mortality, with proposed mechanisms involving ethanol and grape-derived polyphenols, but the evidence remains…

Researchers analyzing 51 longitudinal intervention studies found that reliable generation 2+ DNA methylation biomarkers, particularly those predicting mortality or pace of aging, were the most responsive to interventions aimed at…

A mini-review finds that dietary patterns may influence Alzheimer’s disease through interconnected pathways involving neuroinflammation, insulin resistance, oxidative stress, blood-brain barrier dysfunction, homocysteine, and the gut-brain axis. The authors argue…