New IASLC grading system improves risk stratification in resected lung squamous cell carcinoma

A newly proposed International Association for the Study of Lung Cancer (IASLC) tumor budding-based grading system successfully identified patients with resected lung squamous cell carcinoma (SqCC) at higher risk of…

Continue ReadingNew IASLC grading system improves risk stratification in resected lung squamous cell carcinoma

Study reveals characteristics and outcomes in NSCLC patients harboring class II and III BRAF alterations

Patients with metastatic non-small cell lung cancer (NSCLC) harboring class II and class III BRAF alterations have distinct clinicopathologic and genomic characteristics, with class III alterations potentially associated with worse…

Continue ReadingStudy reveals characteristics and outcomes in NSCLC patients harboring class II and III BRAF alterations

Early consolidative SRT shows value in EGFR-mutant NSCLC with limited brain metastases

Early cranial stereotactic radiotherapy (SRT) administered with first-line osimertinib was associated with improved intracranial control and survival outcomes in patients with EGFR-mutant non-small cell lung cancer (NSCLC) and limited brain…

Continue ReadingEarly consolidative SRT shows value in EGFR-mutant NSCLC with limited brain metastases

Brain MRI surveillance without prophylactic cranial irradiation reduces cognitive failure risk in patients with SCLC

In the SWOG S1827 MAVERICK phase III randomized trial, patients with small-cell lung cancer (SCLC) who underwent regular brain MRI surveillance without prophylactic cranial irradiation (PCI) had significantly better cognitive…

Continue ReadingBrain MRI surveillance without prophylactic cranial irradiation reduces cognitive failure risk in patients with SCLC