Study reveals processes driving DNA damage in prostate cancer
Cancer begins with errors in the DNA inside our cells, and those errors are often more complicated than a handful of mutated genes.
C. diff uses dual-threat sensing system to survive gut stress
The pathogen Clostridioides difficile (C. diff) - a leading cause of hospital-acquired infections - must contend with a variety of threats inside the harsh environment of the gut to survive…
The link between fish and pregnancy hypertension may start before conception
In a nationwide Japanese cohort of more than 86,000 women, higher fish intake before pregnancy was associated with lower odds of early-onset hypertensive disorders of pregnancy, while fish intake during…
Caloric restriction reduces genetic mutations across the mouse genome
Mutations are changes in the molecular "letters" that make up DNA, the genetic blueprint for cells. Mutations build up with age in every cell when DNA is damaged or when…
New genomic language AI model excels in predicting the pathogenicity of genetic variants
More than two decades after scientists first sequenced the entire human genome - all 3 billion "letters," or base pairs, of DNA code - the meaning of much of this…
New genetic map helps track aggressive prostate cancer development
Prostate cancer is the second most common form of cancer among men globally. Yet, we still know relatively little about why the disease develops or why some men live with…
New base editing techniques accurately modify genes in human embryos
A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for…
Study links methylglyoxal stress to immunotherapy resistance in triple-negative cancer
The metabolism of cancer cells may play a key role in their ability to evade the immune system. This is demonstrated by a new study conducted by researchers at the…
Ten minutes of slow running boosts brain function and mood
A growing body of evidence shows that exercise improves mood and cognitive function. However, much of this evidence comes from cycling, which allows researchers to precisely control exercise intensity in…
Digital companion apps help secure long-term habits during GLP-1 therapy
Glucagon-like peptide-1 (GLP-1) medications have revolutionized weight management, yet high dropout rates and rapid weight regain remain significant hurdles for many patients.
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