Zidesamtinib shows strong activity in TKI-naive ROS1-positive non-small cell lung cancer

New results from the global Phase I/II ARROS-1 trial showed clinically meaningful activity with zidesamtinib in patients with advanced or metastatic ROS1-positive non-small cell lung cancer (NSCLC) who had not…

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T-DXd significantly extends progression-free survival in HER2-mutant NSCLC

First-line treatment with trastuzumab deruxtecan (T-DXd) significantly improved progression-free survival compared with pembrolizumab plus platinum-based chemotherapy in patients with advanced or metastatic HER2-mutant non-small cell lung cancer (NSCLC), according to…

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Like your tea or coffee very hot? A study of nearly 1 million adults found a striking cancer link

In pooled prospective data from 977,282 UK adults, preferring tea or coffee “very hot” was associated with more than threefold higher risk of esophageal squamous cell carcinoma compared with preferring…

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An 8-hour eating window stood out for weight loss, but the full picture is more complicated

A pooled analysis of individual data from five time-restricted eating trials involving 124 adults linked shorter eating windows with modestly greater weight loss. Eight-hour TRE was associated with greater weight…

Continue ReadingAn 8-hour eating window stood out for weight loss, but the full picture is more complicated

Tirzepatide vs semaglutide for asthma: the difference was smaller than researchers expected

In a US multicenter electronic health record study, researchers compared tirzepatide with semaglutide in adults with asthma and type 2 diabetes, matching 8,176 patients in each treatment group. Asthma exacerbation…

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What happens to blood pressure during extreme heat? A 4.2 million-visit study offers a clue

In a cross-sectional analysis of more than 4.2 million summer outpatient encounters across US community health centers, same-day extreme heat was associated with small reductions in systolic and diastolic blood…

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A study of ayahuasca users found a mental health pattern researchers cannot yet explain

In a cross-sectional study of 808 Brazilian adults planning to attend ayahuasca ceremonies, greater prior experience with the brew was associated with lower depression, anxiety, and stress scores, as well…

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