Anti-PEG antibodies drive contrasting liposome skin toxicity across species

This new article publication from Acta Pharmaceutica Sinica B discusses how anti-polyethylene glycol antibodies affect the movement of stealth liposomes from blood into skin, revealing contrasting distribution and toxicity patterns…

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Compound YZG-331 leverages gut microbiota to improve sleep in mouse models of insomnia

This new article publication from Acta Pharmaceutica Sinica B discusses how interactions between the investigational compound YZG-331 and the gut microbiota contribute to its sleep-promoting effects in mouse models of…

Continue ReadingCompound YZG-331 leverages gut microbiota to improve sleep in mouse models of insomnia

Topadur’s Phase 2a trial of TOP-N53 for systemic sclerosis-associated digital ulcers advances to next dose levels

Topadur Pharma AG, a Swiss clinical-stage biopharmaceutical company, today announced that the Safety Review Committee of its Phase 2a trial has recommended progression to the next planned dose levels.

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New tool identifies older adults at risk of delirium and falls from anticholinergic medications

Researchers funded by Health Data Research UK (HDR UK) have developed a new tool to help doctors and pharmacists identify older patients at risk of delirium and serious falls associated…

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