Targeting tertiary lymphoid structures for cancer treatment
A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to…
Researchers develop a computational model of grid cell-mediated episodic encoding
Nearly 50 years ago, neuroscientists discovered cells within the brain's hippocampus that store memories of specific locations. These cells also play an important role in storing memories of events, known…
A new AI tool for unlocking the secrets of spatial multi-omics in cancer
A new artificial intelligence-powered tool called MISO (Multi-modal Spatial Omics) can detect cell-level characteristics of cancer by looking at data from extremely small pieces of tissue-some as small as 400…
CGM data offers superior insights into diabetes complications
Data from continuous glucose monitors can predict nerve, eye and kidney damage caused by type 1 diabetes, University of Virginia Center for Diabetes Technology researchers have found. That suggests doctors…
Unmasking the gender bias in Tourette syndrome diagnosis
Tourette syndrome is currently diagnosed about three times more frequently in males than in females. A new study finds that female individuals are less likely to be diagnosed with the…
T-DM1 reduces long-term risk of death in HER2-positive breast cancer patients
In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared…
Unveiling the genetic roots of bicuspid aortic valve
Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease, according…
Leveraging CGP and ctDNA for improved cancer outcomes
Researchers from Iwate Medical University and Tohoku University have revealed that it is possible to predict cancer relapse and treatment response by measuring circulating tumor DNA (ctDNA), in tandem with…
Unlocking the neural basis of overeating
Can memory influence what and how much we eat? A groundbreaking Monell Chemical Senses Center study, which links food memory to overeating, answered that question with a resounding "Yes." Led…
Xenon gas offers potential neuroprotective effects for Alzheimer’s patients
Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and…