As the May 26th CE-IVDR compliance deadline comes into effect, Diagnostics.ai launches the industry's first fully-transparent machine learning platform for clinical real-time PCR diagnostics – demonstrating exactly how each result was achieved, a first for molecular-testing machine learning.

Gene expression leading to alterations in the DNA caused by asbestos exposure may explain the development of Malignant Pleural Mesothelioma (MPM), a rare and aggressive cancer.

A new device that monitors the waste-removal system of the brain may help to prevent Alzheimer's and other neurological diseases, according to a study published today in Nature Biomedical Engineering.

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells.

The tear film coating the eye offers a window into a person's systemic and ocular health, carrying biomarkers such as glucose, electrolytes, and proteins.

Chronic kidney disease (CKD) affects over 800 million people globally and is often diagnosed too late for effective intervention.

America's primary care doctors are burning out, cutting back their hours, and leaving their practices early, driven in part by the demands of handling the flood of digital messages from their patients.

Four leading organizations in lifestyle medicine, obesity medicine, and nutrition-the American College of Lifestyle Medicine (ACLM), the American Society for Nutrition (ASN), the Obesity Medicine Association (OMA), and The Obesity Society (TOS)-have jointly released a clinical advisory titled "Nutritional Priorities to Support GLP-1 Therapy for Obesity."

The number of people living with a history of cancer in the United States is estimated at 18.6 million as of January 1, 2025 and projected to exceed 22 million by 2035, according to a new report, Cancer Treatment and Survivorship Statistics, 2025, led by the American Cancer Society (ACS).

A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international phase 1/2 clinical trial led by researchers at Washington University School of Medicine in St. Louis.

Taking a statin medication is an effective, safe, and low-cost way to lower cholesterol and reduce risk of cardiovascular events. Despite clinicians recommending that many patients with diabetes take statins, nearly one-fifth of them opt to delay treatment. In a new study, researchers found that patients who started statin therapy right away reduced the rate of heart attack and stroke by one third compared to those who chose to delay taking the medication.

Researchers reveal unprecedented insights into insulin resistance that could pave the way for better treatments and earlier detection of type 2 diabetes.

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.

When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the activity of this vital organ. It is often a reversible process that does not cause serious effects on the structure or function of the heart, but if the factor causing cardiac overload becomes chronic, it can lead to pathological hypertrophy with more serious effects (dilatation of the ventricular cavities, alterations in cardiac function, heart failure, etc.).

A new study reveals that a single gene plays a big role in how the liver stores energy, a process that's critical for overall health and for managing diseases like type 2 diabetes. The research focuses on the PPP1R3B gene. This gene tells the liver how to handle energy: store it as glycogen (a form of sugar) or triglycerides (a type of fat).

Successfully treating type 2 diabetes may involve focusing on brain neurons, rather than simply concentrating on obesity or insulin resistance, according to a new study. For several years, researchers have known that hyperactivity of a subset of neurons located in the hypothalamus, called AgRP neurons, is common in mice with diabetes.

A new study shows that people who develop type 1 diabetes in adulthood have an increased risk of cardiovascular disease and death, and that those diagnosed later in life do not have a better prognosis than those diagnosed earlier.

How does obesity affect insulin production? Researchers are shining light on new stages of the ERK pathway.

A new strategy may help prevent or slow the progression of Type 1 diabetes.

A recent study found that six cardiometabolic risk groups previously identified in middle-aged individuals can also be applied to older adults without diabetes. Using data from the KORA F4/FF4 study of people aged 61 to 82, researchers identified clusters with varying risks of developing type 2 diabetes and related complications. One cluster, marked by high inflammatory load and insulin-resistant fatty liver, showed particularly high risk. The study highlights the importance of personalized risk assessment and early prevention strategies even in older age.

Eating a healthy diet as a child is linked to girls having their first menstrual period at an older age than those who consumed a less healthy diet, according to a new study. The findings remained unaltered by the girls' body mass index or height, both of which have been associated with the earlier onset of periods. The study has implications for health in later life as it is well known that women who started their periods at an early age may be at higher risk for diabetes, obesity, breast cancer and diseases of the heart and blood vessels.

Scientists say they have determined that low blood sugar, or hypoglycemia, may promote a breakdown of the blood-retinal barrier, an important boundary that regulates the flow of nutrients, waste and water in and out of the retina.

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 Diabetes, or T2D. The research team focused on the significance of deubiquitinating enzymes, or DUBs, in regulating mitochondrial dynamics within skeletal muscle. Findings suggest that mitochondrial fragmentation can bypass defects in mitophagy, the process by which cells remove damaged mitochondria, to sustain skeletal muscle quality control in patients with T2D. This adaptation may help maintain mitochondrial function despite impaired mitophagy.

Researchers have developed a revolutionary new way to find out the 'true age' of your heart using MRI. A new study shows how an MRI scan can reveal your heart's functional age -- and how unhealthy lifestyles can dramatically accelerate this figure. It is hoped that the findings could transform how heart disease is diagnosed -- offering a lifeline to millions by catching problems before they become deadly. The team say their cutting-edge technique is a 'game changer'.

Semaglutide effectively treats liver disease in two thirds of patients, new research has found.

Researchers investigated the combined effects of bazedoxifene and conjugated estrogens in rat models as an alternative to tamoxifen.

Persistently high blood sugar and insulin resistance significantly increased the risk of worsening functional and structural heart damage during growth from adolescence to young adulthood, a new study shows.

It's no secret that our waistlines often expand in middle-age, but the problem isn't strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases. Exactly how age transforms a six pack into a softer stomach, however, is murky. New research shows how aging shifts stem cells into overdrive to create more belly fat.

Using their novel FRESH 3D bioprinting technique, which allows for printing of soft living cells and tissues, a lab has built a tissue model entirely out of collagen.

Scientists have identified a simple, noninvasive method for assessing blood glucose regulation using continuous glucose monitoring (CGM) data. Their approach, which tracks glucose fluctuations, outperforms traditional markers in predicting diabetes risk. To expand accessibility, they have developed a web application for easy calculation of CGM-based indices.

A data-informed approach to scheduling patient encounters with clinicians can reduce risks associated with diabetes management by up to 19.4%, especially for underserved populations, says new research.

Drugs like Ozempic, other blood sugar-reducing medications, may stave off dementia.

Researchers found that by December 2023, more than 1 in 3 of the medications being started for type 2 diabetes treatment were GLP-1RA-based medications.

A new study has found children born to mothers who experienced gestational diabetes (GDM) during pregnancy are more likely to develop attention-deficient hyperactive disorder (ADHD) and externalizing behavior.

Data-sparse method opens door to personalized nutrition -- without the stool samples.

Researchers conducted a large-scale epidemiological study to explore the potential health benefits of high muscle strength in preventing type 2 diabetes (T2D) across varying levels of genetic risk. The study found that higher muscle strength was associated with over 40% lower risk of T2D, regardless of genetic susceptibility to T2D. The study highlights the importance of maintaining or improving muscle strength as a key strategy for preventing T2D.

Two undergraduate medicine students have led a major study examining how cardioprotective glucose-lowering therapies -- medications that lower blood sugar and reduce the risk of heart disease in people with diabetes -- affect the risk of developing dementia.

The intermittent fasting diet, which involves periods of severe calorie restriction, may be on the way out, as research is suggesting that rather than drastically reducing calories, people can achieve similar metabolic benefits by cutting back on carbs.

Research shows that the biological parents' genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease.

New research has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes -- not the presence of certain fats, but their suppression. The study challenges the conventional belief that a type of fat called ceramides accumulates in blood vessels causing inflammation and health risks. Instead, their findings reveal that when ceramides decrease in endothelial cells lining blood vessels, it can be damaging and cause chronic illnesses. Ironically, the findings could ultimately lead to therapies that maintain high levels of these protective lipids in patients with obesity.

Nearly 40% of patients diagnosed with type 2 diabetes imperil their health by stopping their medication within the first year, diabetes experts warn.

A research team has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes. The results show that high blood pressure can lead to abnormalities in the podocytes, specialized cells in the renal filter, even without other pre-existing conditions such as diabetes. The results underline the importance of early detection and consistent treatment of high blood pressure in order to prevent kidney damage.

Wearable mobile health technology could help people with Type 2 Diabetes (T2D) to stick to exercise regimes that help them to keep the condition under control, a new study reveals. An international team studied the behavior of recently-diagnosed T2D patients in Canada and the UK as they followed a home-based physical activity program, with some participants wearing a smartwatch paired with a health app on their smartphone.

A research team says high blood sugar levels appear to weaken function in key part of brain, mimicking Alzheimer's.

Scientists used advanced data analysis and machine learning to identify the viral proteins that may trigger autoimmune disorders such as type 1 diabetes and rheumatoid arthritis.